clemenzas.com

Monday, August 7, 2006

Dogs can be trained to detect early and late stages of lung and breast cancer accurately according to a study published by California scientists in the little-known scientific journal Integrative Cancer Therapies.

The study took place over the last five years at the Pine Street Foundation, a non-profit organization which conducts evidence-based research on integrative medicine (combining complementary and alternative medicine and mainstream medicine). Michael McCulloch and colleagues used three Labrador Retrievers and two Portuguese Water Dogs, both common pets, that received basic behavioral dog training. The researchers trained the dogs to lie down next to a sample from a cancer patient and to ignore other samples.

The samples used were breath samples from 55 patients with lung cancer and 31 with breast cancer — the two types of cancer with the highest mortality rates in the United States.

After the training phase, the dogs’ accuracy diagnosis was tested in a double-blind experiment. Among lung cancer patients, the sensitivity and specificity were 99% accurate and for breast cancer sensitivity was 88% and specificity 98%. Because these figures seem almost too good to be true, cancer experts are the same time baffled and skeptical. The authors of the study themselves also say replication of the study is needed.

Importantly, this was independent of the cancer stage, meaning the dogs were able to pick up the scent of cancer in its early stages. This is important because in many cases, the success of any treatment depends on early diagnosis. However, the researchers don’t believe this will lead to the use of dogs in the clinic soon, rather they want to find out which chemicals are actually sensed by the canines, because they could be used in laboratory assays. “It’s not like someone would start chemotherapy based on a dog test,” Dr. Gansler of the American Cancer Society said, “They’d still get a biopsy.”.

The researchers were inspired by anecdotal reports about dogs detecting cancer. In 1989, a British women consulted with her family physician because her Dalmatian kept licking a mole on her leg. At biopsy it showed to be malignant melanoma. When diagnosed too late this form of cancer has a poor survival rate, but in this case early surgery was made possible, and the women survived. Prior studies showed that breath samples from patients with lung cancer or breast cancer contain distinct biochemical markers. This provides a basis for the hypothesis that some cancer types produce volatile chemicals that dogs could smell. A study published in the British Medical Journal already proved that dogs could use their exquisite sense of smell to detect bladder cancer in urine samples, but they were only correct in 41% of cases, and another study provided preliminary evidence that dogs could detect melanomas.

This doesn’t mean you can show your breasts to your dog and it will tell you if you have cancer, other physicians caution, and scientists do not advise people to train their dogs to sniff for cancer. Unresolved issues from the study include the fact that subjects were required to breathe deeper than normal, so it’s not sure whether dogs can smell cancer in normal breath. Also, whether this is a permanent skill that would be retained by dogs was not tested.

Finally, there are concerns that could arise over liability issues: who would be responsible when the dog makes a mistake?

Current detection methods for both lung and breast cancer are not flawless. For lung cancer, chest X-ray and sputum cytology (detecting cancer cells in coughed up fluid) fail to detect many early cases, and CT scan produces many false-positive results unless combined with expensive PET scans. Although it might be comparing apples and oranges, a $2.5 million CT scanner has an accuracy of 85 to 90%. Mammography also produces false-positive results, and it may be difficult in women with dense breast tissue. As such, another type of “pet”-scan, using dogs as a biological assay, might prove feasible for screening if supported by further research. Current tests are also expensive so the use of dogs for preliminary cancer testing could prove to be an affordable alternative for countries in the developing world.

Tuesday, August 16, 2011

Alfred Hsing, a US martial artist with Chinese origins, besides having a long history of martial arts training in various styles, such as traditional kung fu, tae kwon do and karate, considers wushu – an athletic sport based on Chinese martial arts – as a form of art that pushes one’s physical limits and stimulates the mind at the same time. After having won the gold medal at the 10th World Wushu Championships, he became international movie star Jet Li’s personal assistant and went on to do stunts, action choreography, and land roles in movies.

Hungarian Wikinews contributor Teemeah has interviewed Alfred Hsing about his views on martial arts, life and Wikipedia.

Friday, July 8, 2016

On Tuesday, Italian police charged homeless forty-year-old Massimo Galioto with the aggravated murder of Beau Solomon, a college student from Wisconsin, US. The police arrested the man after finding the student’s body in the Tiber River in Rome on Monday. The defendant has attorney Michele Vincelli.

According to reports, Massimo Galioto is homeless and lived in a tent under a bridge. Italian police said two witnesses reported they saw someone being thrown from the Garibaldi bridge into the Tiber River. The authorities also reportedly obtained CCTV footage near the bank of the river, showing the incident.

A homeless woman sharing a tent with Massimo Galioto said she saw Massimo Galioto and Beau Solomon fighting each-other, and then saw Beau Solomon fall into the river. The woman alleged Beau Solomon was drunk and the company included two people from North Africa.

On Monday, Italian police found Beau Solomon’s body near Guglielmo Marconi bridge about three miles (five kilometres) downstream from Trastevere, where the student was last seen at about 1AM in G-Bar in Piazza Trilussa on Friday night after his first day in Italy. Solomon was beginning a summer school at John Cabot University. His parents arrived on Monday using emergency passports.

The body had no mobile device or wallet, suggesting to local authorities it was a robbery. The body also had a head wound and bloody shirt, the victim’s 23-year-old brother Cole Solomon told the Milwaukee Journal Sentinel on Monday.

Last week on Friday morning, Beau Solomon’s parents received bank alerts. According to the student’s brother Jake Solomon, the bank told his parents Beau’s bank card was charged “thousands of dollars”. Authorities later confirmed the amount as about 1,500 euro (about US$1700). The credit card of the victim was charged in Milan over 300 miles away from Rome on Friday.

Beau Solomon was aged 19. He came to Italy to attend summer school on Thursday. Beau Solomon did not attend university student orientation next morning, and the institution reported him missing to the local authorities at 9PM.

Tuesday, August 2, 2005

Attorney Jack Thompson, fresh from the “Hot Coffee” controversy, has set his sights on the Electronic Arts (EA) video game The Sims 2 for a mod that removed the blur on nude character models in the game.

Thompson was quoted as saying “Sims 2, the latest version of the Sims video game franchise … contains, according to video game news sites, full frontal nudity, including nipples, penises, labia, and pubic hair.” Factually, the characters resemble that of a child’s dolls. Thompson also accused EA of being in collaboration with the mod makers.

In Electronic Arts’ defense, EA spokesman Jeff Brown said, “Reasonable people understand there is nothing improper in the game. Reasonable people recognise what mods are. A consumer who chooses to use a mod does so without any kind of agreement with the company. There is no nudity. There is nothing improper or vulgar in the Sims 2.”

A mod is third-party add-on to a game. Mods range from minor and subtle changes to the game, to full-fledged “total conversions” which merely use the original game engine to create a very different game.

Monday, March 17, 2014

Nico Rosberg won the opening race of this year’s Formula 1 season in Australia yesterday. TV commentators spoke of “fascination throughout the field” as big names retired and new names proved themselves.

Former champion Lewis Hamilton qualified on pole but problems were evident by the second lap when he received a team radio message telling him “we need to retire… save the engine, save the engine!” Another followed rapidly, however, telling him to “just stay out, stay out, just keep on rolling”. Hamilton left the race on the fourth lap.

Reigning champion Sebastian Vettel did not fare much better, having only qualified twelfth, with engine woes of his own. He too quit the race in the early stages, staying behind to watch the race and, according to commentator and retired Scottish F1 racer David Coulthard, learn what he could from the sidelines.

Vettel and Hamilton were not the only stars retiring early. Veteran racer Felipe Massa was rammed from behind by Kobiashi’s Caterham, sending both cars out and prompting deployment of yellow flags for several laps while the debris was recovered. The crash was triggered by Kobiashi clipping Kimi Raikkonen, damaging the front of Kobiashi’s car. Raikkonen stayed in the race and managed to finish eighth. The first ten cars over the finish line score points towards both the driver’s and constructor’s championships.

Coulthard and fellow commentators believe Kobiashi, who took responsibility for the accident, may receive points on his racer’s licence in a new system to deal with transgressions introduced this year. Kobiashi called the crash “My mistake[… I] should have braked earlier, and I apologise to Felipe”. Massa said Kobiashi “cannot do a start like that, every time” he does so will lead to an accident.

More drama followed shortly after when Valteri Bottas clipped a wall on lap 10, breaking the rim of his back-right wheel. The rim was left on the track, followed shortly thereafter by the tyre off the wheel. The safety car was deployed for several laps until the debris was recovered. Despite the setback Bottas climbed back up the standings and finished in sixth place.

Many drivers, including cars at the front of the pack, took advantage of the safety car period to do pit stops. Some are now considering using less fuel than the maximum allowance in a move the FIA never expected technologically possible when drafting the rules several years ago.

It was a day for débutantes at Albert Park, a street circuit where racing took place in close proximity to busy public roads. Newcomer Kevin Magnussen scored third place on his first F1 race, while fellow rookie Daniil Kvyat came in tenth and became the youngest-ever F1 points scorer. Kvyat takes the record from Vettel by several months while Magnussen becomes the first Dane on an F1 podium.

Not every débutante was so lucky; Caterham driver Marcus Eriksson dropped out of his first race after being radioed “Stop the car, stop the car, engine oil pressure”. Established racers Pastor Maldonado and Romain Grosjean, both Lotus drivers, also stopped with technical trouble. All three cars pulled up at the side of the track on different laps, each triggering yellow flags. Despite the retirements, fourteen cars finished which was more than some commentators were expecting.

Hamilton was upbeat about his retirement, saying “It’s tough for everyone but that’s the way it is” and adding “We’re not the only ones [to have difficulties]”. Vettel was more pessimistic, claiming this is “going to be a long season”. Asked about the cause of his engine troubles, Hamilton said “One of the cylinders, I think, was not firing”.

The race was unusual from start to finish, having been shortened by one lap after the first start was aborted by amber lights instead of just green. The end is more controversial; home driver Daniel Ricciardo scored his first-ever Australian Grand Prix podium finish in second place but was later disqualified for an alleged breach of fuel regulations. Ricciardo had been the first Australian driver to stand on the podium in his home country since Formula 1 brought the event into the championship format used today.

His disqualification is not final, however. His team, Red Bull, have vowed to appeal. If the appeal fails all the drivers below him move up one position, meaning first-time entrant Magnussen will have come in second place and Kvyat will be ninth. That would see Sergio Perez score a point for Force India by moving into tenth. Perez’s race was hampered early by a puncture picked up in the opening lap.

Ricciardo was reported to the stewards by technical delegate Jo Bauer who claimed his car “exceeded consistently the maximum allowed fuel flow of 100kg/h”. 100kg is also the maximum fuel allowed on board cars, a new limit set for this season. The fuel flow rule is also new this year; F1 cars averaged about 170kg/h last year.

Ricciardo was disqualified after five hours of steward deliberations. Red Bull have hit back with a statement saying many teams have found the FIA’s fuel flow meter to be faulty. They say they are “confident the fuel supplied to the engine is in full compliance with the regulations.” Today Andrew Westacott, chief executive of the Australian Grand Prix, said the appeal outcome may not be known for weeks.

Prior to Ricciardo’s disqualification, the remaining point-scorers were Jensen Button in fourth, Fernando Alonso in fifth, Nico Hulkenberg in seventh, and Jean-Eric Vergne in ninth.

Racers and fuel rules were not the only things fresh for this race. Williams are on the back of their worst-ever season and have changed their livery to brighter, whiter cars. Another new innovation is the introduction of red lights on the rear of cars that blink when the vehicle is not using electricity, warning the car behind of possible deceleration. F1 cars also now sport hybrid turbo engines.

Rosberg, speaking after what is his first Australian victory, said it is “Such a pleasure to have such a fast car.” He came a full 24 seconds ahead of Ricciardo. It is also the hundredth victory by an F1 car powered by a Mercedes engine.

“Whatever the outcome I’m really proud of what I did today”, Ricciardo said as he awaited the stewards’ disqualification decision. “There are more positives than negatives”.

Wednesday, February 18, 2009

The United States auto manufacturer Chrysler, which has been badly affected by the ongoing recession, has asked the US government for an additional US$5 billion in aid on top of the four billion it has already received, saying that it plans to fire three thousand employees. At the end of last year, the auto maker had just over 54,000 employees, meaning that the layoffs will equal about six percent of its total workforce.

In addition, Chrysler will cut the Chrysler Aspen, PT Cruiser, and Durango from production.

Another automaker, General Motors (GM), announced that it seeks $16.6 billion in loans from the government, in addition to the $13.4 billion that it has already received. GM plans to lay off 47,000 employees and close five factories. GM says that it might need as much as $30 billion from the US Treasury Department, an increase over their previous estimate of $18 billion. The company has warned that it might run out of money by March if more aid was not given.

Rick Wagoner, GM’s chief executive, described the firm’s plan as “comprehensive, responsive, achievable, and flexible”. “We have a lot of work in front of us, but I am confident it will result in a profitable General Motors,” he said, adding that “today’s plan is significantly more aggressive because it has to be.” GM says that it could be profitable in two years’ time, and might be able to repay all its loans by 2017.

A third US car manufacturer, Ford Motor Company, has said that it can make it through this year without any government aid.

The US Treasury Department will review the car makers’ survival plans for several weeks before a decision is made on whether or not to extend the loans. That decision is due by the end of next month.

Wednesday, January 4, 2006

Israeli prime minister Ariel Sharon (born Ariel Sheinerman), 77, has been admitted to Hadassah hospital in Jerusalem, after suffering what doctors said was a “massive” stroke.

According to reports from Hadassah Ein Karem hospital in Jerusalem, the Prime Minister was put under an anesthetic prior to surgery to address a massive cerebral hemorrhage. He has increased intracranial pressure due to the bleeding.

White House press secretary Scott McClellan said in Thursday’s press briefing that its “thoughts and prayers” are with the Prime Minister, and that the White House will “continue to stay in touch with the government of Israel.”

With Sharon in the hospital, control of Israel has now been transferred to his deputy, vice-premier Ehud Olmert.

Dr. Shlomo Mor-Yosef, director of Hadassah Hospital in Jerusalem said that Sharon suffered “a significant stroke” and that he was “under anesthetic and receiving breathing assistance.” Minutes later, Mor-Yosef said that initial tests showed Sharon suffered a cerebral hemorrhage and that he was suffering “massive bleeding and was being transferred to an operating theater.”

After over 6 hours of surgery Sharon received another CT scan which revealed further bleeding. Sharon was returned to the operating room for additional surgery that is expected to last several hours.

According to Wikipedia, “A stroke or cerebrovascular accident (CVA) occurs when the blood supply to a part of the brain is suddenly interrupted” and many news sources are reporting this situation is life threatening.

Last month on December 18th, Sharon suffered a minor stroke and was admitted to the Hadassah Ein Kerem hospital after feeling unwell driving home and having difficulties with his speech. During his treatment, he was found to have a minor hole in his heart and was scheduled for surgery on January 5th. Sharon was treated and released December 20th.

Sharon’s notorious overeating was a significant risk factor for the health complications he has experienced. Prior to his first stroke, he consumed a meal consisting of hamburgers, lamb, kebabs, steak in chimchurri sauce, and salad. Since that stroke Sharon had lost weight, though he had been known to have his security detail smuggle him pita filled with greasy meat during previous efforts.

On January 6th, in a front-page article in Canada’s The Globe and Mail newspaper, Canadian medical experts questioned the anticoagulent that Sharon had been receiving before his massive stroke, noting that the decision to use it may have cost him his life, and that he would have been unlikely to receive that treatment in Canada. They also noted that his prognosis for recovery is extremely poor.